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Article

Genetics of IL28B and HCV--response to infection and treatment.

Nature reviews. Gastroenterology & hepatology - 29 May 2012

Hayes C Nelson, Imamura Michio, Aikata Hiroshi, Chayama Kazuaki

Abstract excerpt

The IL28B locus attracted the attention of HCV researchers after a series of genome-wide association studies independently identified a strong association between common IL28B polymorphisms and the outcome of PEG-IFN-α plus ribavirin combination therapy in patients chronically infected with HCV genotype 1. This association was subsequently replicated for other HCV genotypes and has been linked to spontaneous...

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Identifiers

PMID: 22641049
DOI: 10.1038/nrgastro.2012.101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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