p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferation.

doi:10.1128/MCB.01363-13

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Article

p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferation.

Molecular and cellular biology - 1 Jun 2014

Bai Feng, Chan Ho Lam, Smith Matthew D, Kiyokawa Hiroaki, Pei Xin-Hai

Abstract excerpt

Pituitary tumors develop in about one-quarter of the population, and most arise from the anterior lobe (AL). The pituitary gland is particularly sensitive to genetic alteration of genes involved in the cyclin-dependent kinase (CDK) inhibitor (CKI)-CDK-retinoblastoma protein (Rb) pathway. Mice het...

Topics

Animals
Body Weight
Carcinogenesis
Cell Proliferation
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinase Inhibitor p19
Diabetes Mellitus, Experimental
Embryo, Mammalian
Epithelial Cells
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fibroblasts

Gene Deletion

Genetic Loci

Infertility, Female

Infertility, Male

Islets of Langerhans

Luteal Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 24687853
DOI: 10.1128/MCB.01363-13
PMCID: PMC4054302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-24687853-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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p19Ink4d is a tumor suppressor and controls pituitary anterior lobe cell proliferation.PMID 24687853Read ↗

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