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Article

ALOX12 in human toxoplasmosis.

Infection and immunity - 1 Jul 2014

Witola William H, Liu Susan Ruosu, Montpetit Alexandre, Welti Ruth, Hypolite Magali, Roth Mary, Zhou Ying, Mui Ernest, Cesbron-Delauw Marie-France, Fournie Gilbert J, Cavailles Pierre, Bisanz Cordelia, Boyer Kenneth, Withers Shawn, Noble A Gwendolyn, Swisher Charles N, Heydemann Peter T, Rabiah Peter, Muench Stephen P, McLeod Rima

Abstract excerpt

ALOX12 is a gene encoding arachidonate 12-lipoxygenase (12-LOX), a member of a nonheme lipoxygenase family of dioxygenases. ALOX12 catalyzes the addition of oxygen to arachidonic acid, producing 12-hydroperoxyeicosatetraenoic acid (12-HPETE), which can be reduced to the eicosanoid 12-HETE (12-hydroxyeicosatetraenoic acid). 12-HETE acts in diverse cellular processes, including catecholamine synthesis,...

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Identifiers

PMID: 24686056
DOI: 10.1128/IAI.01505-13
PMCID: PMC4097613

Genes

ALOX12
LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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