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Article

NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells.

Infection and immunity - 1 Feb 2011

Witola William H, Mui Ernest, Hargrave Aubrey, Liu Susan, Hypolite Magali, Montpetit Alexandre, Cavailles Pierre, Bisanz Cordelia, Cesbron-Delauw Marie-France, Fournié Gilbert J, McLeod Rima

Abstract excerpt

NALP1 is a member of the NOD-like receptor (NLR) family of proteins that form inflammasomes. Upon cellular infection or stress, inflammasomes are activated, triggering maturation of proinflammatory cytokines and downstream cellular signaling mediated through the MyD88 adaptor. Toxoplasma gondii i...

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Identifiers

PMID: 21098108
DOI: 10.1128/IAI.00898-10
PMCID: PMC3028851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21098108-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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