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Article

Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis.

Genes and immunity - 1 Jul 2010

Jamieson S E, Peixoto-Rangel A L, Hargrave A C, Roubaix L-A de, Mui E J, Boulter N R, Miller E N, Fuller S J, Wiley J S, Castellucci L, Boyer K, Peixe R G, Kirisits M J, Elias L de Souza, Coyne J J, Correa-Oliveira R, Sautter M, Smith N C, Lees M P, Swisher C N, Heydemann P, Noble A G, Patel D, Bardo D, Burrowes D, McLone D, Roizen N, Withers S, Bahia-Oliveira L M G, McLeod R, Blackwell J M

Abstract excerpt

Congenital Toxoplasma gondii infection can result in intracranial calcification, hydrocephalus and retinochoroiditis. Acquired infection is commonly associated with ocular disease. Pathology is characterized by strong proinflammatory responses. Ligation of ATP by purinergic receptor P2X(7), encod...

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Identifiers

PMID: 20535134
DOI: 10.1038/gene.2010.31
PMCID: PMC2908187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20535134-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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