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Article

Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity.

Experimental cell research - 1 Jul 2014

Meeths Marie, Chiang Samuel C C, Löfstedt Alexandra, Müller Martha-Lena, Tesi Bianca, Henter Jan-Inge, Bryceson Yenan T

Abstract excerpt

In experimental settings, lymphocyte cytotoxicity has been recognized as a central mechanism for immune defense against infected and neoplastic cells. More recently, molecular determinants of lymphocyte cytotoxicity have been identified through studies of rare, inherited hyperinflammatory and lymphoproliferative syndromes that include hemophagocytic lymphohistiocytosis (HLH). These studies have unraveled a set of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24680986
DOI: 10.1016/j.yexcr.2014.03.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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