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Article

Transcriptional control of early T and B cell developmental choices.

Annual review of immunology - 1 Jan 2014

Rothenberg Ellen V

Abstract excerpt

T and B cells share a common somatic gene rearrangement mechanism for assembling the genes that code for their antigen receptors; they also have developmental pathways with many parallels. Shared usage of basic helix-loop-helix E proteins as transcriptional drivers underlies these common features. However, the transcription factor networks in which these E proteins are embedded are different both in membership...

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Source

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Identifiers

PMID: 24471430
DOI: 10.1146/annurev-immunol-032712-100024
PMCID: PMC3994230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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