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Article

Transcription factor and cytokine regulation of eosinophil lineage commitment

5 Nov 2019

Abstract excerpt

PURPOSE OF REVIEW: Lineage commitment is governed by instructive and stochastic signals, which drive both active induction of the lineage program and repression of alternative fates. Eosinophil lineage commitment is driven by the ordered interaction of transcription factors, supported by cytokine signals. This review summarizes key findings in the study of eosinophil lineage commitment and examines new data...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31688456
DOI: 10.1097/moh.0000000000000552

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