Article
Examining ERBB2 as a candidate gene for susceptibility to leprosy (Hansen's disease) in Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Apr 2014
Araújo Sérgio Ricardo Fernandes, Jamieson Sarra Elisabeth, Dupnik Kathryn Margaret, Monteiro Glória Regina, Nobre Maurício Lisboa, Dias Márcia Sousa, Trindade Neto Pedro Bezerra, Queiroz Maria do Carmo Palmeira, Gomes Carlos Eduardo Maia, Blackwell Jenefer Mary, Jeronimo Selma Maria Bezerra
Abstract excerpt
Leprosy remains prevalent in Brazil. ErbB2 is a receptor for leprosy bacilli entering Schwann cells, which mediates Mycobacterium leprae-induced demyelination and the ERBB2 gene lies within a leprosy susceptibility locus on chromosome 17q11-q21. To determine whether polymorphisms at the ERBB2 loc...
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