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Article

Susceptibility to leprosy is linked to the human NRAMP1 gene.

The Journal of infectious diseases - 1 Jan 1998

Abel L, Sánchez F O, Oberti J, Thuc N V, Hoa L V, Lap V D, Skamene E, Lagrange P H, Schurr E

Abstract excerpt

Leprosy is a debilitating infectious disease of human skin and nerves. Genetic factors of the host play an important role in the manifestation of disease susceptibility. The human NRAMP1 gene is a leprosy susceptibility candidate locus since its murine homologue Nramp1 (formerly Lsh/Ity/Bcg) controls innate resistance to Mycobacterium lepraemurium. In this study, 168 members of 20 multiplex leprosy families were...

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Source

Identifiers

PMID: 9419180
DOI: 10.1086/513830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Susceptibility to leprosy is linked to the human NRAMP1 gene.PMID 9419180Read ↗

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Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease.Semantic proximity Read ↗

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