Within-host bacterial diversity hinders accurate reconstruction of transmission networks from genomic distance data.

Abstract excerpt

The prospect of using whole genome sequence data to investigate bacterial disease outbreaks has been keenly anticipated in many quarters, and the large-scale collection and sequencing of isolates from cases is becoming increasingly feasible. While sequence data can provide many important insights into disease spread and pathogen adaptation, it remains unclear how successfully they may be used to estimate...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Area Under Curve
• Share to Bacterial Infections
• Share to Entropy