Article
The distribution of pairwise genetic distances: a tool for investigating disease transmission.
Genetics - 1 Dec 2014
Worby Colin J, Chang Hsiao-Han, Hanage William P, Lipsitch Marc
Abstract excerpt
Whole-genome sequencing of pathogens has recently been used to investigate disease outbreaks and is likely to play a growing role in real-time epidemiological studies. Methods to analyze high-resolution genomic data in this context are still lacking, and inferring transmission dynamics from such data typically requires many assumptions. While recent studies have proposed methods to infer who infected whom based...
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