Article
K-RAS mutation profile in Puerto Rican patients with colorectal cancer: trends from April 2009 to January 2011.
The International journal of biological markers - 17 Dec 2013
Ruiz-Candelaria Yelitza, Miranda-Diaz Christine, Hunter-Mellado Robert F
Abstract excerpt
The frequency of K-RAS mutations ranges between 30% and 48% among the Caucasian, Asian, and European populations and these mutations are predictors of response to EGFR therapies. We sought to determine the expression of K-RAS gene mutations among colorectal cancer patients in PuertoRico. A retrospective study was conducted to determine the expression of mutant K-RAS among colorectal cancer patients in Puerto Rico...
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