Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel KRAS gene mutations in sporadic colorectal cancer.

PloS one - 1 Jan 2014

Naser Walid M, Shawarby Mohamed A, Al-Tamimi Dalal M, Seth Arun, Al-Quorain Abdulaziz, Nemer Areej M Al, Albagha Omar M E

Abstract excerpt

INTRODUCTION: In this article, we report 7 novel KRAS gene mutations discovered while retrospectively studying the prevalence and pattern of KRAS mutations in cancerous tissue obtained from 56 Saudi sporadic colorectal cancer patients from the Eastern Province. METHODS: Genomic DNA was extracted from formalin-fixed, paraffin-embedded cancerous and noncancerous colorectal tissues. Successful and specific PCR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Models, Molecular
Share to Mutation
Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Asian People

Share to DNA Mutational Analysis

Share to Immunohistochemistry

Source

Open in PubMed Open full text

Identifiers

PMID: 25412182
DOI: 10.1371/journal.pone.0113350
PMCID: PMC4239073

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel KRAS gene mutations in sporadic colorectal cancer.PMID 25412182Read ↗

Discovery of a novel and a rare Kristen rat sarcoma viral oncogene homolog (KRAS) gene mutation in colorectal cancer patients.Semantic proximity Read ↗

Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.Semantic proximity Read ↗

Clinical characteristics and prognostic value of the KRAS mutation in Chinese colorectal cancer patients.Semantic proximity Read ↗

Clinico-pathological study of K-ras mutations in colorectal tumors in Saudi Arabia.Semantic proximity Read ↗

KRAS mutation and its association with clinicopathological features of colorectal cancer patients in Africa: a systematic review and meta-analysis.Semantic proximity Read ↗

Identification of Novel Mutations in Colorectal Cancer Patients using Ampliseq Comprehensive Cancer PanelSemantic proximity Read ↗

Evaluation of KRAS Gene Mutations in Metastatic Colorectal Cancer Patients in Kermanshah Province.Semantic proximity Read ↗

Sanger sequencing in routine KRAS testing: a review of 1720 cases from a pathologist's perspective.Semantic proximity Read ↗

Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patientsSemantic proximity Read ↗

The utility of the Ion Torrent PGM next generation sequencing for analysis of the most commonly mutated genes among patients with colorectal cancer in India.Semantic proximity Read ↗

Associations of KRAS Mutations and Clinical Characteristics of Colorectal Cancer Patients in Indonesia.Semantic proximity Read ↗

Prognostic significance of alterations in KRAS isoforms KRAS-4A/4B and KRAS mutations in colorectal carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.