Article
Novel KRAS gene mutations in sporadic colorectal cancer.
PloS one - 1 Jan 2014
Naser Walid M, Shawarby Mohamed A, Al-Tamimi Dalal M, Seth Arun, Al-Quorain Abdulaziz, Nemer Areej M Al, Albagha Omar M E
Abstract excerpt
INTRODUCTION: In this article, we report 7 novel KRAS gene mutations discovered while retrospectively studying the prevalence and pattern of KRAS mutations in cancerous tissue obtained from 56 Saudi sporadic colorectal cancer patients from the Eastern Province. METHODS: Genomic DNA was extracted...
Topics
- Adult
- Aged
- Aged, 80 and over
- Asian People
- Codon, Nonsense
- Colorectal Neoplasms
- DNA Mutational Analysis
- ErbB Receptors
- Exons
- Female
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Models, Molecular
- Mutation
- Protein Structure, Tertiary
- Receptor, ErbB-2