Article

CRISPR/Cpf1 mediated genome editing enhances <i>Bombyx mori</i> resistance to BmNPV

2020-03-23

Abstract excerpt

CRISPR/Cas12a (Cpf1) is a single RNA-guided endonuclease that provides new opportunities for targeted genome engineering through the CRISPR/Cas9 system. Only AsCpf1 have been developed for insect genome editing, and the novel Cas12a orthologs nucleases and editing efficiency require more study in insect. We compared three Cas12a orthologs nucleases, AsCpf1, FnCpf1, and LbCpf1, for their editing efficiencies and an...

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Identifiers and source

Literature Corpus work: 5dc69c18-ce33-5d7c-a83c-3169871e03ad
DOI: 10.1101/2020.03.23.003368

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