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Article

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression.

Bioinformatics (Oxford, England) - 15 Jul 2014

Marttinen Pekka, Pirinen Matti, Sarin Antti-Pekka, Gillberg Jussi, Kettunen Johannes, Surakka Ida, Kangas Antti J, Soininen Pasi, O'Reilly Paul, Kaakinen Marika, Kähönen Mika, Lehtimäki Terho, Ala-Korpela Mika, Raitakari Olli T, Salomaa Veikko, Järvelin Marjo-Riitta, Ripatti Samuli, Kaski Samuel

Abstract excerpt

MOTIVATION: A typical genome-wide association study searches for associations between single nucleotide polymorphisms (SNPs) and a univariate phenotype. However, there is a growing interest to investigate associations between genomics data and multivariate phenotypes, for example, in gene express...

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Identifiers

PMID: 24665129
DOI: 10.1093/bioinformatics/btu140
PMCID: PMC4080737

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XRCC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24665129-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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