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Article

A modified forward multiple regression in high-density genome-wide association studies for complex traits.

Genetic epidemiology - 1 Sept 2009

Gu Xiangjun, Frankowski Ralph F, Rosner Gary L, Relling Mary, Peng Bo, Amos Christopher I

Abstract excerpt

Genome-wide association studies (GWAS) have been widely used to identify genetic effects on complex diseases or traits. Most currently used methods are based on separate single-nucleotide polymorphism (SNP) analyses. Because this approach requires correction for multiple testing to avoid excessive false-positive results, it suffers from reduced power to detect weak genetic effects under limited sample size. To...

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PMID: 19365845
DOI: 10.1002/gepi.20404
PMCID: PMC2732748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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