Article
Multiple regression methods show great potential for rare variant association tests.
PloS one - 1 Jan 2012
Xu ChangJiang, Ladouceur Martin, Dastani Zari, Richards J Brent, Ciampi Antonio, Greenwood Celia M T
Abstract excerpt
The investigation of associations between rare genetic variants and diseases or phenotypes has two goals. Firstly, the identification of which genes or genomic regions are associated, and secondly, discrimination of associated variants from background noise within each region. Over the last few years, many new methods have been developed which associate genomic regions with phenotypes. However, classical methods...
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