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Article

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

Nature genetics - 1 Jan 2009

Sabatti Chiara, Service Susan K, Hartikainen Anna-Liisa, Pouta Anneli, Ripatti Samuli, Brodsky Jae, Jones Chris G, Zaitlen Noah A, Varilo Teppo, Kaakinen Marika, Sovio Ulla, Ruokonen Aimo, Laitinen Jaana, Jakkula Eveliina, Coin Lachlan, Hoggart Clive, Collins Andrew, Turunen Hannu, Gabriel Stacey, Elliot Paul, McCarthy Mark I, Daly Mark J, Järvelin Marjo-Riitta, Freimer Nelson B, Peltonen Leena

Abstract excerpt

Genome-wide association studies (GWAS) of longitudinal birth cohorts enable joint investigation of environmental and genetic influences on complex traits. We report GWAS results for nine quantitative metabolic traits (triglycerides, high-density lipoprotein, low-density lipoprotein, glucose, insulin, C-reactive protein, body mass index, and systolic and diastolic blood pressure) in the Northern Finland Birth...

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Source

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Identifiers

PMID: 19060910
DOI: 10.1038/ng.271
PMCID: PMC2687077

Genes

AR
FADS1
FADS2
MTNR1B
NR1H3
PANK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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