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Article

Sparse reduced-rank regression for integrating omics data.

BMC bioinformatics - 3 Jul 2020

Hilafu Haileab, Safo Sandra E, Haine Lillian

Abstract excerpt

BACKGROUND: The problem of assessing associations between multiple omics data including genomics and metabolomics data to identify biomarkers potentially predictive of complex diseases has garnered considerable research interest nowadays. A popular epidemiology approach is to consider an association of each of the predictors with each of the response using a univariate linear regression model, and to select...

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PMID: 32620072
DOI: 10.1186/s12859-020-03606-2
PMCID: PMC7333421

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