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Article

A robust multifactor dimensionality reduction method for detecting gene-gene interactions with application to the genetic analysis of bladder cancer susceptibility.

Annals of human genetics - 1 Jan 2011

Gui Jiang, Andrew Angeline S, Andrews Peter, Nelson Heather M, Kelsey Karl T, Karagas Margaret R, Moore Jason H

Abstract excerpt

A central goal of human genetics is to identify susceptibility genes for common human diseases. An important challenge is modelling gene-gene interaction or epistasis that can result in nonadditivity of genetic effects. The multifactor dimensionality reduction (MDR) method was developed as a mach...

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Identifiers

PMID: 21091664
DOI: 10.1111/j.1469-1809.2010.00624.x
PMCID: PMC3057873

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21091664-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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