Article
Inhibitors of the tick-borne, hemorrhagic fever-associated flaviviruses.
Antimicrobial agents and chemotherapy - 1 Jun 2014
Flint Mike, McMullan Laura K, Dodd Kimberly A, Bird Brian H, Khristova Marina L, Nichol Stuart T, Spiropoulou Christina F
Abstract excerpt
No antiviral therapies are available for the tick-borne flaviviruses associated with hemorrhagic fevers: Kyasanur Forest disease virus (KFDV), both classical and the Alkhurma hemorrhagic fever virus (AHFV) subtype, and Omsk hemorrhagic fever virus (OHFV). We tested compounds reported to have antiviral activity against members of the Flaviviridae family for their ability to inhibit AHFV replication. 6-Azauridine...
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