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A diarylamine derived from anthranilic acid inhibits ZIKV replication

27 Nov 2019

Abstract excerpt

Abstract Zika virus (ZIKV) is a mosquito-transmitted Flavivirus, originally identified in Uganda in 1947 and recently associated with a large outbreak in South America. Despite extensive efforts there are currently no approved antiviral compounds for treatment of ZIKV infection. Here we describe the antiviral activity of diarylamines derived from anthranilic acid (FAMs) against ZIKV. A synthetic FAM (E3)...

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PMID: 31776405
DOI: 10.1038/s41598-019-54169-z

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