Article
The evolution of the unstable cancer genome.
Current opinion in genetics & development - 1 Feb 2014
Burrell Rebecca A, Swanton Charles
Abstract excerpt
Cancer next-generation sequencing and genomics studies published over the last five years have provided unprecedented insights into the forces shaping cancer genome evolution. In particular, these studies have revealed a high level of heterogeneity not only between different tumours, but also within individual tumours; the 'cancer genome' may evolve along several independent trajectories within a single tumour....
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