Article
[Tumour genomics: an unstable landscape].
Bulletin du cancer - 1 Oct 2008
Moyret-Lalle Caroline, Falette Nicole, Grelier Gaël, Puisieux Alain
Abstract excerpt
Oncogenesis and tumour progression are caused by the progressive accumulation of genetic and epigenetic abnormalities in pre-cancerous and cancerous cells, conferring increased capabilities of proliferation and survival. Recent technological advances, including the development of CGH arrays and high-throughput sequencing, have made it possible to map the genetic landscape of human cancers. Molecular...
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