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Article

Variability of the transferrin receptor 2 gene in AMD.

Disease markers - 1 Jan 2014

Wysokinski Daniel, Blasiak Janusz, Dorecka Mariola, Kowalska Marta, Robaszkiewicz Jacek, Pawlowska Elzbieta, Szaflik Jerzy, Szaflik Jacek Pawel

Abstract excerpt

Oxidative stress is a major factor in the pathogenesis of age-related macular degeneration (AMD). Iron may catalyze the Fenton reaction resulting in overproduction of reactive oxygen species. Transferrin receptor 2 plays a critical role in iron homeostasis and variability in its gene may influence oxidative stress and AMD occurrence. To verify this hypothesis we assessed the association between polymorphisms of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24648608
DOI: 10.1155/2014/507356
PMCID: PMC3933306

Genes

TFR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variability of the transferrin receptor 2 gene in AMD.PMID 24648608Read ↗

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