Article
An association between environmental factors and the IVS4+44C>A polymorphism of the DMT1 gene in age-related macular degeneration.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Jul 2012
Wysokinski Daniel, Zaras Malgorzata, Dorecka Mariola, Waszczyk Maja, Szaflik Jerzy, Blasiak Janusz, Szaflik Jacek P
Abstract excerpt
BACKGROUND: Age-related macular degeneration (AMD) is an ocular disease affecting macula - the central part of the retina, resulting in the degeneration of photoreceptors and retinal epithelium and causing severe central vision impairment. The pathophysiology of the disease is not completely known, but a significant role is attributed to genetic factors. The contribution of oxidative stress in AMD as a trigger of...
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