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Article

Lack of association between the c.544G>A polymorphism of the heme oxygenase-2 gene and age-related macular degeneration.

Medical science monitor : international medical journal of experimental and clinical research - 1 Aug 2011

Wysokinski Daniel, Synowiec Ewelina, Chmielewska Marta, Wozniak Katarzyna, Zaras Małgorzata, Sklodowska Anna, Blasiak Janusz, Szaflik Jerzy, Szaflik Jacek Pawel

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is a primary cause of blindness among the elderly in developed countries. The nature of AMD is complex and includes both environmental and hereditary factors. Oxidative stress is thought to be essential in AMD pathogenesis. Iron is suggested to be implicated in the pathogenesis of AMD through the catalysis of the production of reactive oxygen species, which can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21804464
DOI: 10.12659/msm.881906
PMCID: PMC3539623

Genes

HMOX2

Variants

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