Article
An association of transferrin gene polymorphism and serum transferrin levels with age-related macular degeneration.
Experimental eye research - 1 Jan 2013
Wysokinski Daniel, Danisz Katarzyna, Blasiak Janusz, Dorecka Mariola, Romaniuk Dorota, Szaflik Jerzy, Szaflik Jacek Pawel
Abstract excerpt
Age-related macular degeneration (AMD) is a degenerative disease of the eye, triggered by the damage of the macular cells. In the Western world it is the most frequent cause of blindness in the elderly. Oxidative stress is proved to play a key role in AMD pathogenesis and since iron accumulation has been found in AMD maculas, it may accelerate the oxidative processes in this tissue. In the present work we...
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