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Article

An association between polymorphism of the heme oxygenase-1 and -2 genes and age-related macular degeneration.

Molecular biology reports - 1 Mar 2012

Synowiec Ewelina, Szaflik Jerzy, Chmielewska Marta, Wozniak Katarzyna, Sklodowska Anna, Waszczyk Maja, Dorecka Mariola, Blasiak Janusz, Szaflik Jacek Pawel

Abstract excerpt

Iron may be implicated in the generation of oxidative stress by the catalyzing the Haber-Weiss or Fenton reaction. On the other hand, oxidative stress has been implicated in the pathogenesis of age-related macular degeneration (AMD) and heme oxygenase-1 (HO-1), encoded by the HMOX1 gene and heme...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21647550
DOI: 10.1007/s11033-011-0955-3
PMCID: PMC3271228

Genes

HMOX2
HMOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21647550-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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