Article
Role of MMP-2 (-1306 C/T) Polymorphism in Age-Related Macular Degeneration.
Ophthalmic genetics - 1 Jun 2016
Liutkeviciene Rasa, Lesauskaite Vaiva, Zaliaduonyte-Peksiene Diana, Sinkunaite-Marsalkiene Giedre, Zaliuniene Dalia, Mizariene Vaida, Gustiene Olivija, Jasinskas Vytautas, Tamosiunas Abdonas
Abstract excerpt
PURPOSE: To determine if the frequency of the MMP-2 (-1306 C/T) genotype has an influence on the development of early age-related macular degeneration (AMD). METHODOLOGY: The study enrolled 387 patients with early AMD and a random sample of 682 healthy persons (control group). The genotyping of MMP-2 (-1306 C/T) was carried out using the real-time polymerase chain reaction method. RESULTS: The analysis of the...
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