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Article

Analysis of KRAS mutations in cases of metastatic colorectal cancer at a single institution in Tochigi, Japan.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2014

Saito Natsuko, Tomita Shigeki, Ichikawa Kazuhito, Mitomi Hiroyuki, Imura Johji, Fujimori Takahiro

Abstract excerpt

OBJECTIVE: Colorectal cancer patients bearing wild-type KRAS benefit from anti-epidermal growth factor receptor (EGFR) antibody treatment. Since clinical studies showed the efficacy of anti-EGFR antibody treatment for metastatic colorectal cancer (mCRC), we analyzed KRAS mutations in mCRC to gain insight into the association between these mutations and clinicopathological characteristics. METHODS: KRAS mutations...

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Identifiers

PMID: 24642668
DOI: 10.1159/000357812

Genes

KRAS
EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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