BLK and BANK1 variants and interactions are associated with susceptibility for primary Sjögren's syndrome and with some clinical features.

doi:10.1016/j.cellimm.2021.104320

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Article

BLK and BANK1 variants and interactions are associated with susceptibility for primary Sjögren's syndrome and with some clinical features.

Cellular immunology - 1 May 2021

Montúfar-Robles Isela, Lara-García Samantha, Barbosa-Cobos Rosa Elda, Vargas-Alarcón Gilberto, Hernández-Molina Gabriela, Fragoso José M, Cabello-Gutiérrez Carlos, Reyes-Cetina Ivonne Leticia, Arenas-Silva Ivonne, Cruz-Mayor Kerly Janina, Concha-Del Río Luz Elena, De Anda-Turati Maribel, Sánchez-Tlapalcoyoatl Ana, Cheja-Kalb Rashel, Hubbe-Tena Claudia, Lima Guadalupe, Mendoza-Rincón Jorge Flavio, Ramírez-Bello Julián

Abstract excerpt

BLK and BANK1 in primary Sjögren's syndrome (pSS) have scarcely been evaluated and the results are inconclusive. The aim of our study was to determine whether single nucleotide variants (SNVs) located within BLK or BANK1 are associated with susceptibility, clinical and serological features, and smoking in pSS. BLK rs13277113A/G, BANK1 rs10516487G/A and rs3733197G/A were genotyped in 203 cases and 424 controls...

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PMID: 33756160
DOI: 10.1016/j.cellimm.2021.104320

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