Article
Interleukin-6 gene polymorphism, chronic stress and atherosclerosis: interleukin-6-174G>C polymorphism, chronic stress and risk of early atherosclerosis in the Cardiovascular Risk in Young Finns Study.
Journal of psychosomatic research - 1 Apr 2014
Chumaeva Nadja, Hintsanen Mirka, Pulkki-Råback Laura, Jokela Markus, Juonala Markus, Lehtimäki Terho, Raitakari Olli T, Keltikangas-Järvinen Liisa
Abstract excerpt
OBJECTIVE: Interleukin-6 protein has been suggested as a mediator connecting chronic stress and cardiovascular diseases. We investigated whether the functional G174C polymorphism (rs1800795) of interleukin-6 gene is associated with vital exhaustion, a measure of chronic stress, or with preclinical atherosclerosis. METHODS: Associations between the interleukin-6-174G>C polymorphism, preclinical atherosclerosis,...
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