Article
Polymorphism in the IL6 promoter region is associated with the risk factors and markers of subclinical atherosclerosis in men: The Cardiovascular Risk in Young Finns Study.
Atherosclerosis - 1 Apr 2009
Hulkkonen Janne, Lehtimäki Terho, Mononen Nina, Juonala Markus, Hutri-Kähönen Nina, Taittonen Leena, Marniemi Jukka, Nieminen Tuomo, Viikari Jorma, Raitakari Olli, Kähönen Mika
Abstract excerpt
OBJECTIVE: Inflammatory factors modify the risk of coronary heart disease. Promoter region genetic polymorphism of inflammatory cytokine interleukin-6 (IL6 -174 G>C) is associated with the variation of IL-6 production. We investigated whether IL6 -174 G>C associates with the risk factors of atherosclerosis and carotid artery compliance (CAC) in young subjects. METHODS AND RESULTS: As part of the Cardiovascular...
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