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Article

Association of interleukin 6 -174 G/C polymorphism with coronary artery disease and circulating IL-6 levels: a systematic review and meta-analysis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Dec 2021

Rai Himanshu, Colleran Roisin, Cassese Salvatore, Joner Michael, Kastrati Adnan, Byrne Robert A

Abstract excerpt

INTRODUCTION: Circulating IL-6 levels and at least one polymorphic form of IL6 gene (IL6 -174 G/C, rs1800795) have been shown to be independently associated with coronary artery disease (CAD) by several investigators. Despite more than 12 published meta-analyses on this subject, association of -174 G/C with CAD, especially amongst distinct ancestral population groups remain unclear. We, therefore, conducted a...

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Identifiers

PMID: 34595552
DOI: 10.1007/s00011-021-01505-7
PMCID: PMC8572816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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