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Article

Genetic suppression of β2-adrenergic receptors ameliorates tau pathology in a mouse model of tauopathies

13 Mar 2014

Abstract excerpt

Accumulation of the microtubule-binding protein tau is a key event in several neurodegenerative disorders referred to as tauopathies, which include Alzheimer's disease, frontotemporal lobar degeneration, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. Thus, understanding the molecular pathways leading to tau accumulation will have a major impact across multiple neurodegenerative...

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PMID: 24626633
DOI: 10.1093/hmg/ddu116

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