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Article

Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration

17 May 2021

Abstract excerpt

Abstract Tauopathies are a group of neurodegenerative diseases characterized by the alteration/aggregation of TAU protein, for which there is still no effective treatment. Therefore, new pharmacological targets are being sought, such as elements of the endocannabinoid system (ECS). We analysed the occurrence of changes in the ECS in tauopathies and their implication in the pathogenesis. By integrating gene...

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PMID: 34001284
DOI: 10.1186/s40478-021-01196-5

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