Article
Admixture analysis of spontaneous hepatitis C virus clearance in individuals of African descent.
Genes and immunity - 1 Apr 2014
Wojcik G L, Thio C L, Kao W H L, Latanich R, Goedert J J, Mehta S H, Kirk G D, Peters M G, Cox A L, Kim A Y, Chung R T, Thomas D L, Duggal P
Abstract excerpt
Hepatitis C virus (HCV) infects an estimated 3% of the global population with the majority of individuals (75-85%) failing to clear the virus without treatment, leading to chronic liver disease. Individuals of African descent have lower rates of clearance compared with individuals of European descent and this is not fully explained by social and environmental factors. This suggests that differences in genetic...
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