Article
Sudan's complex genetic admixture history drives adaptation to malaria in Sudanese Copts.
Proceedings of the National Academy of Sciences of the United States of America - 20 Jan 2026
Vilà-Valls Laura, Garcia-Calleja Jorge, Prado-Martinez Javier, Bosch Elena, Andrés Aida M, Netea Mihai G, Comas David, Hassan Hisham Y
Abstract excerpt
Sudan lies at the crossroads of Africa and the Middle East, with rich cultural, linguistic, and ecological diversity shaped by a complex demographic history. We present a whole-genome sequencing (WGS) study of Sudanese populations, analyzing high-coverage genomes (~30×) from 125 individuals representing five ethnolinguistic groups across three language families. Our results reveal deep population structure,...
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