Genetic polymorphism in IL28B is associated with spontaneous clearance of hepatitis C virus genotype 4 infection in an Egyptian cohort.

doi:10.1093/infdis/jir536

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Article

Genetic polymorphism in IL28B is associated with spontaneous clearance of hepatitis C virus genotype 4 infection in an Egyptian cohort.

The Journal of infectious diseases - 1 Nov 2011

Kurbanov Fuat, Abdel-Hamid Mohamed, Latanich Rachel, Astemborski Jacquie, Mohamed Mostafa, Mikhail Nabiel Mh, El-Daly Mai, El-Kafrawy Sherif, Thomas David L, Thio Chloe L

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) around IL28B are associated with spontaneous hepatitis C virus (HCV) clearance of genotypes 1 and 3 in white and African-American populations. This study investigated whether the IL28B SNP (rs12979860) is associated with spontaneous clearance of HCV, principally genotype 4, in 162 Egyptians (80 with clearance). The protective C allele was more common in those with...

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PMID: 21933876
DOI: 10.1093/infdis/jir536
PMCID: PMC3182308

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