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Article

Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.

BMC genomics - 13 Mar 2014

Castle John C, Loewer Martin, Boegel Sebastian, de Graaf Jos, Bender Christian, Tadmor Arbel D, Boisguerin Valesca, Bukur Thomas, Sorn Patrick, Paret Claudia, Diken Mustafa, Kreiter Sebastian, Türeci Özlem, Sahin Ugur

Abstract excerpt

BACKGROUND: Tumor models are critical for our understanding of cancer and the development of cancer therapeutics. Here, we present an integrated map of the genome, transcriptome and immunome of an epithelial mouse tumor, the CT26 colon carcinoma cell line. RESULTS: We found that Kras is homozygously mutated at p.G12D, Apc and Tp53 are not mutated, and Cdkn2a is homozygously deleted. Proliferation and stem-cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24621249
DOI: 10.1186/1471-2164-15-190
PMCID: PMC4007559

Genes

EGFR
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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