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MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer

30 Jan 2023

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) primary tumours are molecularly classified into four consensus molecular subtypes (CMS1-4). Genetically engineered mouse models aim to faithfully mimic the complexity of human cancers and, when appropriately aligned, represent ideal pre-clinical systems to test new drug treatments. Despite its importance, dual-species classification has been limited by the lack of a reliable...

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PMID: 36717674
DOI: 10.1038/s41416-023-02157-6

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