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Article

Genomic profiling of patient-derived colon cancer xenograft models.

Medicine - 1 Dec 2014

Lee Won-Suk, Kim Hye-Youn, Seok Jae Yeon, Jang Ho Hee, Park Yeon Ho, Kim So-Young, Shin Dong Bok, Hong Suntaek

Abstract excerpt

Recent evidence suggests that patient derived xenograft (PDX) models can maintain certain pathological and molecular features of the original disease. However, these characterizations are limited to immunohistochemistry or by tissue microarray analysis. We conducted a high-throughput sequencing of primary colon tumor and PDX has not been reported yet. Fresh primary colon cancer tissues that originate from surgery...

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Identifiers

PMID: 25526474
DOI: 10.1097/MD.0000000000000298
PMCID: PMC4603094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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