Article

Tumor-immune Profiling of CT-26 and Colon 26 Syngeneic Mouse Models Reveals Mechanism to Anti-PD-1 response

2021-06-18

Abstract excerpt

<h4>Background: </h4> Immune checkpoint blockade (ICB) therapies have changed the paradigm of cancer therapies. However, anti-tumor response of the ICB is insufficient for many patients and limited to specific tumor types. Despite many preclinical and clinical studies to understand the mechanism of anti-tumor efficacy of ICB, the mechanism is not completely understood. Harnessing preclinical tumor models is one wa...

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Literature Corpus work: 2536b43a-2dd3-5279-8382-55f1bdfb02f5
DOI: 10.21203/rs.3.rs-600447/v1

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