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Article

Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective.

PLoS genetics - 1 Jan 2012

DeVeale Brian, van der Kooy Derek, Babak Tomas

Abstract excerpt

In contrast to existing estimates of approximately 200 murine imprinted genes, recent work based on transcriptome sequencing uncovered parent-of-origin allelic effects at more than 1,300 loci in the developing brain and two adult brain regions, including hundreds present in only males or females. Our independent replication of the embryonic brain stage, where the majority of novel imprinted genes were discovered...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22479196
DOI: 10.1371/journal.pgen.1002600
PMCID: PMC3315459

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