Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pilus proteins from Streptococcus pyogenes stimulate innate immune responses through Toll‐like receptor 2

6 Feb 2022

Abstract excerpt

The group A Streptococcus (GAS) pilus is a long, flexible, hair-like structure anchored to the cell surface that facilitates the adherence of GAS to host cells, thus playing a critical role in initiating infections. Because of its important role in GAS virulence, the pilus has become an attractive target for vaccine development. While current research mainly focuses on pilus function and its potential as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Neonatal and Maternal Infections
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35124861
DOI: 10.1111/imcb.12523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pilus proteins from Streptococcus pyogenes stimulate innate immune responses through Toll‐like receptor 2PMID 35124861Read ↗

Toll-like receptor (TLR) 2 mediates inflammatory responses to oligomerized RrgA pneumococcal pilus type 1 protein.Semantic proximity Read ↗

T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 Streptococcus pyogenes.Semantic proximity Read ↗

The Group A Streptococcus serotype M2 pilus plays a role in host cell adhesion and immune evasion.Semantic proximity Read ↗

Genetics, Structure, and Function of Group A Streptococcal PiliSemantic proximity Read ↗

Responses of innate immune cells to group A StreptococcusSemantic proximity Read ↗

Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulenceSemantic proximity Read ↗

Structural Conservation, Variability, and Immunogenicity of the T6 Backbone Pilin of Serotype M6 Streptococcus pyogenesSemantic proximity Read ↗

A pneumococcal pilus influences virulence and host inflammatory responses.Semantic proximity Read ↗

Relevance of Pili in Pathogenic Streptococci Pathogenesis and Vaccine DevelopmentSemantic proximity Read ↗

Group A Streptococcus Encounters with Host MacrophagesSemantic proximity Read ↗

Streptococcal M Protein: A Multipotent and Powerful Inducer of InflammationSemantic proximity Read ↗

A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.