Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practice

1 Jan 2017

Abstract excerpt

Click here and here to see the linked articlesIntroductionThis study assessed KRAS mutation detection and functional characteristics across 13 distinct technologies and assays available in clinical practice, in a blinded manner.MethodsFive distinct KRAS-mutant cell lines were used to study five clinically relevant KRAS mutations: p.G12C, p.G12D, p.G12V, p.G13D and p.Q61H. 50 cell line admixtures with low (50 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations
Share to Molecular Biology Techniques and Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29018576
DOI: 10.1136/esmoopen-2017-000235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Key differences between 13 KRAS mutation detection technologies and their relevance for clinical practicePMID 29018576Read ↗

KRAS and BRAF Mutation Analysis in Routine Molecular DiagnosticsSemantic proximity Read ↗

A Multicenter Blinded Study to Evaluate KRAS Mutation Testing Methodologies in the Clinical SettingSemantic proximity Read ↗

Identification of KRASG12C Mutations in Circulating Tumor DNA in Patients With Cancer.Semantic proximity Read ↗

Multi-Center Evaluation of the Fully Automated PCR-Based Idylla™ KRAS Mutation Assay for Rapid KRAS Mutation Status Determination on Formalin-Fixed Paraffin-Embedded Tissue of Human Colorectal CancerSemantic proximity Read ↗

KRAS mutation testing in clinical practice.Semantic proximity Read ↗

Improving the Limit of Detection for Sanger Sequencing: A Comparison of Methodologies for <i>KRAS</i> Variant DetectionSemantic proximity Read ↗

Molecular epidemiology and diagnostics of KRAS mutations in human cancer.Semantic proximity Read ↗

Landscape of KRAS G12C , Associated Genomic Alterations, and Interrelation With Immuno-Oncology Biomarkers in KRAS -Mutated CancersSemantic proximity Read ↗

KRAS G12C in advanced NSCLC: Prevalence, co-mutations, and testing.Semantic proximity Read ↗

Performance evaluation comparison of 3 commercially available PCR-based KRAS mutation testing platforms.Semantic proximity Read ↗

Single-molecule detection of cancer mutations using a novel PCR-LDR-qPCR assay.Semantic proximity Read ↗

KRAS mutations detection methodology: from RFLP to CRISPR/Cas based methods.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.