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QIAGEN Therascreen KRAS RGQ Assay, QIAGEN KRAS Pyro Assay, and Dideoxy Sequencing for Clinical Laboratory Analysis of KRAS Mutations in Tumor Specimens.

Laboratory medicine - 1 Feb 2016

Alqahtani Qamra M, Crowley Ann, Rapp Sharleen, Cushman-Vokoun Allison M

Abstract excerpt

OBJECTIVE: To compare the performance of assays used to assess KRAS mutations in tumor specimens. METHODS: We analyzed DNA extracted from 30 formalin-fixed paraffin-embedded (FFPE) tumor specimens using the QIAGEN Therascreen KRAS RGQ and QIAGEN Pyro reagents, with dideoxy sequencing (colloquially considered to be the gold standard) as the reference method. RESULTS: We detected 22 codon 12 or 13 KRAS mutations...

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PMID: 26732779
DOI: 10.1093/labmed/lmv009

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KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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