Article
A comparability study of 5 commercial KRAS tests.
Diagnostic pathology - 16 Apr 2010
Oliner Kelly, Juan Todd, Suggs Sid, Wolf Michael, Sarosi Ildiko, Freeman Daniel J, Gyuris Tibor, Baron Will, Bakker Andreas, Parker Alex, Patterson Scott D
Abstract excerpt
BACKGROUND: Activating mutations in the KRAS gene occur frequently in human tumors, including colorectal carcinomas; most mutations occur in codons 12 and 13. Mutations in KRAS have been associated with poor response to anti-epidermal growth factor receptor antibodies. Therefore, an accurate and readily available analysis of KRAS mutational status is needed. The aim of this study was to evaluate concordance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
